Surface Enhanced Raman Spectroscopy (SERS)



  • Indian Institute of Technology, Delhi has developed a handheld Surface Enhanced Raman Spectroscopy (SERS)-based platform for early diagnosis of dengue and also gives dengue test results within one hour (rapid diagnosis).
  • The research work was funded by IMPRINT India programme of the Ministry of Education.

Difference between RT-PCR and SERS

Surface Enhanced Raman Spectroscopy (SERS)

Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)

  • It is a surface-sensitive technique that enhances Raman scattering by molecules adsorbed on rough metal surfaces or by nanostructures such as plasmonic-magnetic silica nanotubes.
  • Early diagnosis of dengue is the key to prevent deterioration of a patient’s health.
  • It is a conventional diagnostic tool.
  • It is a time-taking process and it also requires expensive equipment and reagents for the diagnosis of dengue.
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